My current area of research is focused on understanding controls of secondary metabolism in Fusarium venenatum with the aim of disabling production of deleterious secondary metabolites and generating improved strains for production of nutritionally enhanced mycoprotein.
My background is in plant molecular biology, genetic transformation and the use of in vitro methods enabling improvement in clonal crops, including strawberry, top fruit, and fungi.
5. I am currently developing transformation technologies for fruit crops with the aim of enabling transformation of recalcitrant genotypes and for transgene-free gene editing.
Wilson F., Harrison R. (2021). CRISPR/Cas9 mediated editing of the Quorn fungus Fusarium venenatum A3/5 by transient expression of Cas9 and sgRNAs targeting endogenous marker gene PKS12. Fungal Biol Biotechnol 8, 15.
NELLIST C.F., Vickerstaff R.J., Sobczyk M.K., Marina-Montes C., Wilson F.M., Simpson D.W., Whitehouse A.B. and Harrison R.J. (2019). Quantitative trait loci controlling Phytophthora cactorum resistance in the cultivated octoploid strawberry (Fragaria x ananassa). Horticulture Research. Volume: 6(60), 1-14.
Wilson F, Harrison K, Armitage AD, Simkin, AJ, Harrison RJ. (2019). CRISPR/Cas9-mediated mutagenesis of phytoene desaturase in diploid and octoploid Strawberry. BMC Plant Methods.
Andrew D Armitage, Andrew Taylor, Maria K Sobczyk, Laura Baxter, Bethany P.J. Greenfield, Helen Bates, Fiona Wilson, Alison Jackson, Sascha Ott, Richard Harrison, John P. Clarkson. (2018). Pangenomic analysis reveals pathogen-specific regions and novel effector candidates in Fusarium oxysporum f.sp.cepae. (preprint) BioRxiv.
L Antanaviciute, N Šurbanovski, N Harrison, K J McLeary, D W Simpson, F Wilson, D J Sargent & R J Harrison. (2015). Mapping QTL associated with Verticillium dahliae resistance in the cultivated strawberry (Fragaria × ananassa) Horticulture Research 2. 15009.